Genomic integrity in the male germ line: evidence in support of the disposable soma hypothesis
- Creator: Xavier, Miguel J. , Mitchell, Lisa A. , McEwan, Kristen E. , Scott, Rodney J. , Aitken, R. John
- Resource Type: journal article
- Date: 2018
Epididymal CYP2E1 plays a critical role in acrylamide-induced DNA damage in spermatozoa and paternally mediated embryonic resorptions
- Creator: Katen, Aimee Lee , Sipila, Petra , Mitchell, Lisa A. , Stanger, Simone J. , Nixon, Brett , Roman, Shaun D.
- Resource Type: journal article
- Date: 2017
Electrophilic aldehydes generated by sperm metabolism activate mitochondrial reactive oxygen species generation and apoptosis by targeting succinate dehydrogenase
- Creator: Aitken, R. John , Whiting, Sarah , De Iuliis, Geoffrey N. , McClymont, Samantha , Mitchell, Lisa A. , Baker, Mark A.
- Resource Type: journal article
- Date: 2012
Sperm motility is lost in vitro as a consequence of mitochondrial free radical production and the generation of electrophilic aldehydes but can be significantly rescued by the presence of nucleophilic thiols
- Creator: Aitken, John R. , Gibb, Zamira , Mitchell, Lisa A. , Lambourne, Sarah R. , Connaughton, Haley S. , De Iuliis, Geoffry N.
- Resource Type: journal article
- Date: 2012
Phosphoinositide 3-kinase signalling pathway involvement in a truncated apoptotic cascade associated with motility loss and oxidative DNA damage in human spermatozoa
- Creator: Koppers, Adam J. , Mitchell, Lisa A. , Wang, Ping , Lin, Minjie , Aitken, R. John
- Resource Type: journal article
- Date: 2011
Proteomic and functional analysis of human sperm detergent resistant membranes
- Creator: Nixon, Brett , Mitchell, Lisa A. , Anderson, Amanda L. , McLaughlin, Eileen A. , O'Bryan, Moira K. , Aitken, R. John
- Resource Type: journal article
- Date: 2011
Sperm-zona pellucida interaction: molecular mechanisms and the potential for contraceptive intervention
- Creator: Dun, Matthew D. , Mitchell, Lisa A. , Aitken, R. John , Nixon, Brett
- Resource Type: book chapter
- Date: 2010
DNA damage in human spermatozoa is highly correlated with the efficiency of chromatin remodeling and the formation of 8-hydroxy-2′-deoxyguanosine, a marker of oxidative stress
- Creator: De Iuliis, Geoffry N. , Thomson, Laura K. , Mitchell, Lisa A. , Finnie, Jane M. , Koppers, Adam John , Hedges, Andrew , Nixon, Brett , Aitken, R. John
- Resource Type: journal article
- Date: 2009
Investigation of the role of SRC in capacitation-associated tyrosine phosphorylation of human spermatozoa
- Creator: Mitchell, Lisa A. , Nixon, Brett , Baker, Mark A. , Aitken, R. John
- Resource Type: journal article
- Date: 2008
The identification of mouse sperm-surface-associated proteins and characterization of their ability to act as decapacitation factors
- Creator: Nixon, Brett , MacIntyre, David A. , Mitchell, Lisa A. , Gibbs, Gerard M. , O'Bryan, Moira , Aitken, R. John
- Resource Type: journal article
- Date: 2006